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15 Regional Sandwiches That Should Be World Famous

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Every corner of America has a sandwich worth traveling for, but some are still waiting for their moment in the spotlight. This list brings together 15 unforgettable regional classics, each with a story, a strong following, and an unforgettable bite. If you’re looking for something different, these sandwiches will take your tastebuds on a cross-country adventure.

Fried Pork Tenderloin Sandwich

A massive pork tenderloin sandwich.

Maddy Alewine / Them Bites

Indiana’s fried pork tenderloin is all about a huge, crispy cutlet that spills over the bun, piled with pickles and onions. It’s a Midwestern rite of passage. Get the recipe.

Pepperoni Rolls

Finished pepperoni rolls on a baking sheet.

Maddy Alewine / Them Bites

West Virginia miners made this simple roll with sticks of pepperoni tucked inside soft dough. It’s grab-and-go lunch at its finest, and completely unique to the Mountain State. Try it here.

Pork Chop Sandwich

A beautifully fried pork tenderloin sandwich on a cutting board.

Maddy Alewine / Them Bites

Montana’s contribution is a fried pork chop in a bun. It’s straightforward, hearty, and perfect for a quick meal after a day outdoors. See how it’s made.

Hot Brown Sandwich

A Kentucky hot brown looking absolutely gorgeous in a cast iron pan.

Maddy Alewine / Them Bites

Louisville’s legendary open-faced turkey sandwich, covered with bacon and creamy Mornay sauce, then broiled until golden. It’s rich, decadent, and a Kentucky essential. Try the original.

Shrimp Po Boy

A delicious looking shrimp po boy with shredded lettuce, pickles, and tomato.

Maddy Alewine / Them Bites

Louisiana’s favorite street food: crunchy fried shrimp in a French roll with lettuce, tomato, pickles, and remoulade. You won’t forget this one. See the recipe.

Olive Burger

An oozing olive burger that is popular in Michigan.

Maddy Alewine / Them Bites

Michigan’s quirky classic loads green olive mayo atop a juicy beef patty. It’s briny, beefy, and surprisingly addictive. Try a bite.

Primanti Brothers Sandwich

A primanti brothers sandwich.

Maddy Alewine / Them Bites

Pittsburgh’s icon stacks coleslaw and fries right in the sandwich, alongside meats, cheeses, and tomato. Complete meal in every bite. Meet the legend.

Sonoran Hot Dog

Two sonoran dogs hanging out on a cutting board.

Maddy Alewine / Them Bites

Tucson, Arizona’s creation is a bacon-wrapped hot dog topped with pinto beans, tomatoes, onions, jalapeños, and a drizzle of crema. It’s spicy, creamy, and crunchy all at once. Build your own.

Bobbie Sandwich

An open face bobbie sandwich. You can see a lot of cranberry sauce on top.

Maddy Alewine / Them Bites

Delaware’s most famous sandwich is Thanksgiving on a roll: turkey, cranberry sauce, stuffing, and mayo. It’s comfort food year-round. Taste the tradition.

St. Paul Sandwich

A St. Paul sandwich split in half that is showing the cross section.

Maddy Alewine / Them Bites

This St. Louis original fills white bread with an egg foo young patty, lettuce, pickles, and mayo. It’s a Chinese-American classic gone Midwestern. Try something new.

Loose Meat Sandwich

A loose meat sandwich that has the bun off of the top and is showing the insides. You can see a pile of chopped white onion on the side.

Maddy Alewine / Them Bites

Iowa’s no-nonsense beef sandwich lets you pick your own toppings. It’s comfort food that never fails. Get the recipe.

Cudighi Sandwich

An open face shot of a cudighi sandwich.

Maddy Alewine / Them Bites

Upper Peninsula Michigan’s spicy Italian sausage, topped with marinara and mozzarella on a hoagie roll. It’s hearty and always hits the spot. Dig in.

Jucy Lucy

A cross section of a Jucy Lucy burger with cheese oozing out.

Maddy Alewine / Them Bites

Minneapolis’s Jucy Lucy is a burger with the cheese inside the patty. Bite in, and you get a river of melted cheese with every mouthful. Experience the ooze.

North Shore Beef

A classic three way with a ton of James River BBQ sauce everywhere.

Maddy Alewine / Them Bites

From Massachusetts, this roast beef sandwich is thinly sliced, piled high, and best with “three-way” style;cheese, mayo, and barbecue sauce. Discover the classic.

Sailor Sandwich

A meaty Sailor boy sandwich.

Maddy Alewine / Them Bites

Richmond, Virginia’s rye bread classic, layered with pastrami, grilled knackwurst, Swiss cheese, and a good schmear of mustard. Set sail.



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